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1.
Discovery of the Potent and Selective ATR Inhibitor Camonsertib (RP-3500).
J Med Chem
; 67(4): 2349-2368, 2024 Feb 22.
Article
in English
| MEDLINE | ID: mdl-38299539
2.
RP-3500: A Novel, Potent, and Selective ATR Inhibitor that is Effective in Preclinical Models as a Monotherapy and in Combination with PARP Inhibitors.
Mol Cancer Ther
; 21(2): 245-256, 2022 02.
Article
in English
| MEDLINE | ID: mdl-34911817
3.
Identification of RP-6685, an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of Polθ.
J Med Chem
; 65(19): 13198-13215, 2022 10 13.
Article
in English
| MEDLINE | ID: mdl-36126059
4.
Pharmacological characterization of MK-7246, a potent and selective CRTH2 (chemoattractant receptor-homologous molecule expressed on T-helper type 2 cells) antagonist.
Mol Pharmacol
; 79(1): 69-76, 2011 Jan.
Article
in English
| MEDLINE | ID: mdl-20943773
5.
Azaindoles as potent CRTH2 receptor antagonists.
Bioorg Med Chem Lett
; 21(2): 841-5, 2011 Jan 15.
Article
in English
| MEDLINE | ID: mdl-21185722
6.
New indole amide derivatives as potent CRTH2 receptor antagonists.
Bioorg Med Chem Lett
; 21(11): 3471-4, 2011 Jun 01.
Article
in English
| MEDLINE | ID: mdl-21515053
7.
Applying the pro-drug approach to afford highly bioavailable antagonists of P2Y(14).
Bioorg Med Chem Lett
; 21(14): 4366-8, 2011 Jul 15.
Article
in English
| MEDLINE | ID: mdl-21689930
8.
The identification of 4,7-disubstituted naphthoic acid derivatives as UDP-competitive antagonists of P2Y14.
Bioorg Med Chem Lett
; 21(10): 2836-9, 2011 May 15.
Article
in English
| MEDLINE | ID: mdl-21507640
9.
Synthesis and SAR of pyrimidine-based, non-nucleotide P2Y14 receptor antagonists.
Bioorg Med Chem Lett
; 21(10): 2832-5, 2011 May 15.
Article
in English
| MEDLINE | ID: mdl-21507642
10.
Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases.
Bioorg Med Chem Lett
; 21(1): 288-93, 2011 Jan 01.
Article
in English
| MEDLINE | ID: mdl-21106375
11.
The C3a receptor antagonist SB 290157 has agonist activity.
Immunol Lett
; 100(2): 139-45, 2005 Sep 15.
Article
in English
| MEDLINE | ID: mdl-16154494
12.
Identification of N,N-disubstituted phenylalanines as a novel class of inhibitors of hepatitis C NS5B polymerase.
J Med Chem
; 46(8): 1283-5, 2003 Apr 10.
Article
in English
| MEDLINE | ID: mdl-12672227
13.
Discovery of novel P2Y14 agonist and antagonist using conventional and nonconventional methods.
J Biomol Screen
; 16(9): 1098-105, 2011 Oct.
Article
in English
| MEDLINE | ID: mdl-21821827
14.
Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: Sulfonamides.
Bioorg Med Chem Lett
; 14(3): 793-6, 2004 Feb 09.
Article
in English
| MEDLINE | ID: mdl-14741291
15.
Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 2: tertiary amides.
Bioorg Med Chem Lett
; 14(3): 797-800, 2004 Feb 09.
Article
in English
| MEDLINE | ID: mdl-14741292
16.
HCV NS5B polymerase-bound conformation of a soluble sulfonamide inhibitor by 2D transferred NOESY.
Bioorg Med Chem Lett
; 14(21): 5333-7, 2004 Nov 01.
Article
in English
| MEDLINE | ID: mdl-15454222
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